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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6619 | Desmethyl Erlotinib hydrochloride | OSI420,OSI-420,DesMethyl Erlotinib (CP-473420) HCl,CP-473420,Desmethyl Erlotinib,OSI 420 | EGFR , Drug Metabolite |
Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells... | |||
T0373L | Erlotinib hydrochloride | OSI-744,NSC 718781,Erlotinib HCl,CP-358774 | EGFR , Autophagy |
Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer. |